Friday, November 30, 2012

Gilda's Club name change insult to late comedian?

Paintings imagining comedian Gilda Radner in recognizable locations in Madison hang on the wall inside the cancer support group Gilda's Club Madison on Wednesday, Nov. 27, 2012, in Middleton, Wis. The Madison-area chapter of the national group is the latest to change its name to the Cancer Support Community, a move its director said was necessary because young people don't know who Radner was. (AP Photo/Scott Bauer)

Paintings imagining comedian Gilda Radner in recognizable locations in Madison hang on the wall inside the cancer support group Gilda's Club Madison on Wednesday, Nov. 27, 2012, in Middleton, Wis. The Madison-area chapter of the national group is the latest to change its name to the Cancer Support Community, a move its director said was necessary because young people don't know who Radner was. (AP Photo/Scott Bauer)

In a May 4, 2012 photo Bonnie Hanson polishes furniture in the "Baba Wawa" room at Gilda's Club in Middleton, Wis. The Madison-area chapter of the national cancer support group Gilda's Club is the latest affiliate to change its name, saying many no longer know who comedienne Gilda Radner was. (AP Photo/Wisconsin State Journal, M.P. King.)

FILE - In this Sept. 27, 1983 file photo, actress and comedienne Gilda Radner holds up copies of her book, "Roseanne Roseannadanna's "Hey, Get Back To Work," at a New York bookstore. The Madison, Wis.-area chapter of Gilda's Club is the latest to change its name to the Cancer Support Community, a move its director said was necessary because young people don't know who Radner was. (AP Photo/Suzanne Vlamis)

A framed image of comedian Gilda Radner hangs on the wall inside the cancer support group Gilda's Club Madison on Wednesday, Nov. 27, 2012, in Middleton, Wis. The Madison-area chapter of the national group is the latest to change its name to the Cancer Support Community, a move its director said was necessary because young people don't know who Radner was. (AP Photo/Scott Bauer)

A June 8, 2012 photo shows the exterior of Gilda's Club in Middleton, Wis. The Madison-area chapter of the national cancer support group Gilda's Club is the latest affiliate to change its name, saying many no longer know who comedienne Gilda Radner was. (AP Photo/The Capitol Times, Michelle Stocker.)

MIDDLETON, Wis. (AP) ? Remember Roseanne Roseannadana? Or Emily Litella? Or Baba Wawa?

Younger generations might not recognize the characters popularized by comedian Gilda Radner. Nor might they remember Radner herself, an original cast member of "Saturday Night Live" who died 23 years ago and for whom a national cancer support group is named.

That's troubling to the Madison-area chapter of Gilda's Club, which decided to change its name in part because of concern that many don't know who Radner was. But the move prompted outrage from some Radner fans ? who saw it as a slight to a woman who confronted cancer with dignity and humor ? and led other chapters across the nation to hastily reaffirm they have absolutely no intention of changing their names.

Lannia Syren Stenz, the Madison-area club's executive director, said her organization decided to change its name to Cancer Support Community Southwest Wisconsin after it realized that most college students were born after Radner died in 1989.

"We are seeing younger and younger adults who are dealing with a cancer diagnosis," Stenz told the Wisconsin State Journal. "We want to make sure that what we are is clear to them and that there's not a lot of confusion that would cause people not to come in our doors."

Her comments angered some Radner fans, who let loose a storm of criticism on the organization's Facebook page.

"The only educating you're doing is teaching kids that when they die from cancer, their name will be erased from history in 20 years because the next generation doesn't know who they are. Way to give them hope!" wrote Mark Warneke, 44, a full-time college student in Arlington, Texas.

He told The Associated Press that taking Radner's name off the foundation was an insult to her memory.

Stenz referred questions from the AP to Linda House, executive vice president of the national group. House said there was no evidence that young people are unfamiliar with Radner and the name change was motivated by the desire to make the organization's mission clear. She called Stenz's comments "not accurate, period."

"Gilda Radner is very much a part of the fiber of this organization," House said. "There has never been an intent and there is no intent to lose Gilda as part of the organization."

Stenz's club held a ceremony Thursday to mark the name change, which will be phased it over the next month.

Radner, who was diagnosed with ovarian cancer in 1986, sought support from The Wellness Community in California and wrote about her experience in her book "It's Always Something," a reference to one of her characters' catch-phrases.

Her friends and family started Gilda's Club in 1991 on the East Coast to honor her legacy. The name was inspired by something Radner said after her diagnosis: "Having cancer gave me membership in an elite club I'd rather not belong to."

Gilda's Club Worldwide merged with The Wellness Community in 2009, and the joint headquarters in Washington changed its name to the Cancer Support Community. Local chapters were given the choice of keeping their names or switching to Cancer Support Community, House said.

The 56 chapters around the world deliver $40 million a year in free care to about 1 million cancer patients and their families, she said. Of those chapters, 20 are known as Gilda's Club, three are Wellness Community and 23 are Cancer Support Community.

Changing the chapters' names made sense to Ron Nief, a professor at Beloit College in southern Wisconsin who has made a career out of studying how different generations view the world differently. He said it could become harder for Gilda's Club to attract donations as fewer people remember seeing Radner on TV.

"I think we all want to keep our traditions alive," he said, "but there comes a reality in this case of what does this group represent and how do we raise money for it."

Radner's husband, actor Gene Wilder, said he didn't like the name change but he understood it. He said if he had to break the news to his late wife she might ask, "Do they have to throw me out?"

"I'd say, 'It's not throwing you out, honey, it's getting more money.' And she'd say, 'OK, I guess if they have to, they have to,'" he said. "It's too bad. I wish it weren't so. But I understand."

The Wellness Center where Radner once sought support in Los Angeles was one of the groups that updated its name. Julia Forth, the marketing director of what's now called the Cancer Support Community Benjamin Center, said people who get sick Google the word cancer, so it helps to have that word in the name.

Other organizations were adamant about keeping the Gilda's Club name. LauraJane Hyde, who runs the Chicago chapter, said her group has spent 15 years teaching people that Radner's name was synonymous with cancer support, in the same way people know what Starbucks sells even though "coffee" isn't in its name.

"A lot of people feel very passionately about the name," she said. "We will lose donations if we change it."

Radner remains a strong presence at the Madison-area club even without her name on the building in the suburb of Middleton. Paintings and drawings of Radner line the walls. One depicts her on top of Madison's state Capitol. Another imagines her sitting along the shores of Lake Mendota on the University of Wisconsin-Madison campus.

The meeting rooms are named after her Saturday Night Live characters, including New York-street smart reporter Roseanne Roseannadana, out-of-sync editorialist Emily Litella and speech-impeded talk show host Baba Wawa, a parody of Barbara Walters.

___

Ramde reported from Milwaukee and can be reached at dramde(at)ap.org. Associated Press researcher Rhonda Shafner contributed to this report from New York. Follow Scott Bauer on Twitter at http://twitter.com/sbauerAP.

Newsday

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-11-29-Gilda's%20Club-Name%20Change/id-946f0cb9f44a45e699d9d073d71d4d13

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Importance of Business Strategic Coming up with | Hugo Hosting

Business strategic planning is a single thing that your business really should have to be in a position to obtain it. When you do not return up with an efficient arrange or technique that you are going to use, your company will not be capable to attain the ambitions that you want it to get to. The most efficient fashion to offer with a organization is to preliminary established a aim for it and then device a means for you to get to that certain objective. Hold in mind that each 1 your steps should lead to the most effective interest of your enterprise as a outcome of you will notice in the future that this is often what incredibly issues. Nevertheless if you learn oneself sensation dropped due to the fact you do not grasp where you require to commence, you can request aid from some firms in coming up with a strategic coming up with for your business.

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When you are previously certain that you are going to be in a position to take care of the strategic coming up with period well, you?ll now shift on to undertaking it. In these planning periods, you will be helped by pros in coming up with the objectives so as to be in a position to scale again long term expenditures, making your organization model less difficult, mastering regarding methods that will aid you managing the performances of your foreseeable future staff and in helping you turn into the greatest leader that you can most likely be.

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No matter whether or not you are doing it on your personal or not, a organization strategic creating is unquestionably 1 in each and every of the most motives why a confident organization finds its indicates at the higher of the market.

Related posts:

  1. Understanding Strategic Planning And Its Importance In Business Success
  2. The Importance of Strategic Planning Software ? Why Do So Many Strategic Plans Fail?
  3. Merger Acquisition ? Services Of Strategic Importance
  4. Why You Need Strategic Planning To Survive In Business
  5. Best Strategic Business Marketing Tips

Source: http://www.hugohosting.com/importance-of-business-strategic-coming-up-with.html

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Thursday, November 29, 2012

Social Customer Service (Featured in Airline Business ...

social CS

Editor?s Note: This article was featured in Airline Business (September Issue), contributed by CEO of SimpliFlying, Shashank Nigam. For a soft copy of the original article, please see here.?

?

Airlines that have innovated customer service though online media have elevated passenger expectations to a level that sets a high standard for others to follow, according to Shashank Nigram of SimpliFlying

Late last year a friend had a bad experience with Delta Air Lines during his honeymoon.

A number of things went wrong ? from being assigned a seat away from his new bride, to the couple being ignored by flight attendants. When he called the customer service hotline he was put on hold for a long time and transferred from one department to another. In the end, his concerns were hardly addressed by Delta staff.

Frustrated, he blogged about his encounter with Delta and dropped me a note asking for help. I suggested he tweet to @Deltaassist. Much to his surprise, he received a reply on Twitter within 10min, saying Delta was looking into his case. Within 24 hours, he was given a $100 voucher for the inconvenience he suffered during his flight.

Some might claim this to be a one- off case but thanks to social media real- time customer service is coming of age in the airline industry.

Social media benchmarking company Unimetric.com says that if you send a tweet to Delta Air Lines, you are likely to get a reply within 11min, while if you tweet JetBlue with a problem, it will address it within 17min. Also, KLM will reply within an hour and Virgin America is known to solve passengers? problems in-flight while they are connected to the internet at 35,000ft.

Through social media, airline customer service has become real-time and customers expect answers around the clock. In fact, travel social media company Eezeer says 71.4% of con- sumer tweets to airlines are customer- service-related. The growth of calls to customer service centres is projected to decline this year, with social conversation numbers occasionally equalling phone calls.

First and foremost, this is because customers no longer have to go through the hassle of holding on the phone to customer services and expect to get answers more easily, especially for queries that are not time sensitive.

The responsive, interactive and open nature of social media helps customers feel comfortable to ask more questions and get all doubts cleared ? not always possible on the phone. The airline can understand better what the most worrying issues for customers are and how its service can be improved.

Apart from the undeniable benefits social media provides, customers now expect most brands to respond to them on social media, an almost equally compelling reason for airlines to have social media customer service initiatives. As seen in the case of the Royal Brunei Airlines emergency landing of flight BI098 in April this year, the internet and social media are unmatched in providing speedy information, especially in times of crisis.

Consumers are often pleased to receive acknowledgement, even if the resolution is not immediate. Hence, the key to success in customer service via social media lies in a quick response before reaching resolution. Several airlines are now innovating in this space.

What can you learn from the airlines that provide the best customer service on social media?

Share local knowledge and provide personal attention

One of the most innovative tools being used by Ireland?s CityJet is its Twitter concierge. The programme aims to provide personalised recommendations to travellers who request them. This helps drive their goals in engagement, customer service and revenue. Goals of social customer service programmes need to translate back to the core metrics of the brand and marketing.

Prepare to scale

KLM and Delta Air Lines have more than 30 people dedicated to providing customer service through social media. That sort of commitment is often needed because once you set the customers? expectations that they can reach you online, that is the medium they prefer ? especially when something goes wrong. That is when all these resources come in handy. Of course, if you are unable to dedicate such resources, you might want to work with a social media call-centre provider such as InterGlobe Technologies.

Be where you are needed

Delta was one of the first airlines to dedicate resources to social media, recognising the importance of acknowledgement and resolution. The need to give its customers what they want led to a guaranteed reply within 10min on Twitter, plus a dedicated social media customer service and support in Spanish and Portuguese.

?

The post Social Customer Service (Featured in Airline Business) appeared first on SimpliFlying.

Author information

Li Guen heads the communications and marketing functions at SimpliFlying where she drives corporate branding efforts and industry research initiatives. A PR enthusiast, Li Guen returned to SimpliFlying after a stint with Weber Shandwick working with clients including Rolls-Royce, Changi Airport Group and P&G.In her free time, Li Guen likes trekking mountains in Asia. You can tweet her at @SimpliGuen or email her at guen@simpliflying.com.

Source: http://connect.phocuswright.com/2012/11/social-customer-service-featured-in-airline-business/

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Trading for Armageddon | Aquire Advisors

Why ?troubled? markets shouldn?t affect your investment strategy.

by Reese Harper, President, CFP?
November 21, 2012

Many of our clients have asked how the ?fiscal cliff? and presidential elections will impact their portfolios. Let?s start by defining the ?cliff? and then we?ll review a few big mistakes investors make during volatile markets. In short, the ?cliff? refers to a combination of expiring tax cuts and across-the-board government spending cuts scheduled to become effective Dec. 31, 2012. Many people fear these taxes and cuts will push our fragile economy over the ?cliff?. As you review the alarming headlines, please remember journalists can be heavy on emotion and light on facts. While the problems we face are very real, the media doesn?t always offer objective, tempered viewpoints when competing for your attention. Post election, I?m personally optimistic that a compromise will be reached and that Congress will rise to the occasion and take positive steps towards putting our fiscal house in order. But when planning for retirement, we must take a broader view than what may or may not occur over the next 40+ days.

1. You?re playing the long game.

We invest our savings in companies and governments around the globe. We diversify into many different countries and industries; as the global market changes, we adjust our investments to reflect the changes the world is experiencing. This allows us to reduce risk, harvest returns, and stay current with rapidly advancing economies. Nothing has occurred that changes our investment philosophy. By holding a substantial emergency fund, saving plenty of money, and measuring our time horizon, we are able to be patient, capturing returns from the equity (stock) market at precisely the time when other investors are moving to cash, and paying a premium for safety.? Successful investors don?t react to bad news, they execute a strategy, and follow through during difficult times.

2. Information is reflected in prices.

Making changes to your portfolio after receiving publicly available information has not proven to be a successful investment strategy. Widely accessible information is quickly priced into the value of our portfolios. The pending fiscal cliff and debt crisis has been rumbling down the track for years. Since this information is widely known, we can conclude that these concerns?a dysfunctional congress, and looming fiscal cliff?are already priced into our current portfolios.

3. Treat your retirement plan like your mortgage.

We pay off our homes using a formal plan, but we typically plan for retirement with informal parameters. When paying off our home we use a precise schedule and allocate exact dollars for principle, interest, property taxes, and insurance. When planning for retirement investors should establish a monthly plan as regimented as their mortgage. Don?t miss any retirement ?payments? or you will incur penalties and increased interest, delaying your financial independence.

4. Sharp market changes are?impossible to predict.

Trying to predict when to enter and exit the market is extremely difficult. Today investors worry about the potential downside of owning equities, the risk of loss. But what of tomorrow?s fear? What about inflation, rising interest rates, and increasing health care expenses? Remember, the lower prices travel, the greater the increase in expected returns. The downward journey is not very fun, but when negative returns appear it is doubly important to remain invested since the inflection point cannot be identified in advance. In March, 2009, it was nearly inconceivable that equity prices were on the verge of one of the strongest advances in history, yet it happened. Many investors made the tactical decision to avoid losses by exiting the market, yet they missed one of the quickest and sharpest rebounds ever experienced in stocks.? Investors who purchased stocks during this period cashed in on the best Black Friday sale in decades. That particular advance, and the subsequent years? advances, carried most portfolios to levels greater than before the meltdown began. Through prudent financial planning, our clients continued to build up emergency reserves, and purchase stocks at historically low levels.

5. Timing the market is highly speculative.?

Deciding when to leave the market is hard, but it?s doubly hard to decide when to get back in. While it may seem obvious that equity prices are destined to decline over the near term, it is impossible to know the extent and duration of that decline or whether it will even occur the way it has been portrayed by the financial press. Anxious investors who wish to avoid losses are simply trading one set of anxieties for another. Experience suggests that investors who exit in similar situations rarely, if ever, re-enter the equity markets. Those who do gather the courage to ?get back in? will be faced with the new fear that every succeeding sell-off, no matter how short, might be the beginning of another significant downturn. This cycle of entering and exiting the market is one of the reasons why the average investor?s return is so poor during a lifetime. Owning equities carries the risk of loss, which is why knowing the appropriate volatility for your portfolio is so important. Risk is equal to reward.

6. Inflation.?

A well-designed financial plan will allow the interest and income from investments to support living expenses of the retiree. The goal of every investor is to outlive their retirement assets. We have often pointed out, one of the most effective means to accomplish this goal is to maintain at least some exposure to stocks. While returns on high-quality, fixed-income instruments and cash are usually stable, they are currently at real levels (adjusted for inflation) of less than zero. It is important to remember that inflation ticks away each and every day, increasing the cost of everything we need to live. Avoiding the ?risk? of equities is also avoiding the reward and this is a recipe for problems. Fixed retirement income + rising costs = not enough income. More clearly stated, a failed retirement plan.

7 Stay the course.?

Staying the course in a decreasing market is hard, especially if you?re convinced you ?see it coming?. We have already endured what may be the most difficult period for equity markets in many of our lives (2008-2009). A functioning, global market doesn?t ever fall to zero. At some point prices are low enough to spur demand. As prices decline, expected returns increase. Selling out or significantly reducing equity exposure during this time is not a viable investment strategy and this presents the distinct possibility of being left behind when the recovery occurs.

Investors? portfolios should be constructed to balance the need for return with the ability to handle volatility. We work with our clients to build a strong, multi-year emergency fund which allows them to maintain exposure to stocks during the more volatile times.

Start early, save as much as you can, and don?t get distracted by the noise along the way.

Copyright ? 2012 by Aquire Advisors.

This article is part of an ongoing initiative to educate our clients and to help them meet their investing goals.

Source: http://aquireadvisors.com/trading-for-armageddon/

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US seeks expanded military ties with Indonesia - KTTC Rochester ...

WASHINGTON (AP) - A senior U.S. official says Washington should expand its military ties with Indonesia, befitting a relationship between two robust democracies.

Top diplomat for East Asia, Kurt Campbell, said those ties have grown in recent years, but not fast enough.

Campbell was speaking Tuesday at a gathering of the U.S.-Indonesia Society in Washington.

The U.S. severed military ties for several years after of Indonesia's bloody crackdown in East Timor in 1999. Jakarta has since sought to professionalize and modernize its military. Key U.S. restrictions on engagement with Indonesia's feared special forces were lifted in 2010.

Human rights groups say Indonesia's military abuse continues, particularly in the restive province of west Papua.

Campbell also advocated deeper ties between the two governments and praised Jakarta's leadership in regional diplomacy.

Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.kttc.com/story/20199534/us-seeks-expanded-military-ties-with-indonesia

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Rdio Revamps Its iOS And Android Apps Bringing Improved Looks, Navigation, New Playback Controls & More

Rdio-iPhone-Lineup_ENStreaming music startup?Rdio?continues its battle with Spotify, today updating its two flagship mobile applications for iOS and Android. The new apps have been redesigned with a cleaner layout, introduce new navigational elements, and add other clever features to enhance the user experience - like the ability to pick up playing a track from where you left off on another platform, for example.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/0Ooqu_749Ho/

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Wednesday's Powerball jackpot hits $550 million

As the Powerball frenzy continues, people across the nation are rushing out to buy their ticket to a dream, but winning the jackpot can sometime translate to major losses. NBC's Erica Hill reports on the lottery "curse" and two September Powerball winners how their lives have changed, for better and for worse.

By NBC News staff and wire services

Updated at 1:35 p.m. ET: Someone could win $550 million in Wednesday night's Powerball drawing, the largest in the game's history.

The jackpot jumped up from half a billion dollars on Wednesday, according to the Powerball website. The new jackpot would carry a cash value of $360.2 million before taxes.

Lottery officials say they now believe there is a 75 percent chance the winning numbers will be drawn Wednesday night, The Associated Press reported. Powerball is played across 42 states, plus Washington, D.C., and the Virgin Islands.


As big as this week's Powerball jackpot is, it's not the largest lottery prize ever. That mark is held by the $656 million Mega Millions jackpot that was split by three ticket buyers earlier this year. The previous biggest Powerball prize was $365 million in 2006, shared by several ConAgra Foods workers in Lincoln, Neb.

Since the jackpot is an estimate, the prize money could be increased as the drawing nears, the AP reported.

Related: 11 things more likely to happen than winning the Powerball jackpot

There were no Powerball winners for Saturday's drawing, in which $325 million was up for grabs.?The winning numbers Saturday were 22-32-37-44-50 with Powerball 34, according to the Powerball lottery's website. There were 10 winners of $1 million and one winner of $2 million.

The huge jackpot has brought a flood of ticket sales. "It?s been crazy," said the manager of a 7-Eleven convenience store in Westminster, Colo., that sold 2,000 tickets in 11 hours on Tuesday, Reuters reported.

Ticket buyers are not only dreaming of living large, but already brewing ways in which they might quit their job.

"I was thinking maybe I should hire a marching band to help me (quit)," Joe Cooke of Illinois told Reuters, after buying $50 in Powerball tickets Wednesday morning. "Or maybe I'll just walk right into office and moon him." Cooke, 29, fields customer service calls for a financial institution, which he describes as listening to "rich, mean people" complaining all day, Reuters reported.

The Associated Press and Reuters contributed to this report.

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Source: http://usnews.nbcnews.com/_news/2012/11/28/15515086-powerball-jackpot-hits-550-million-for-wednesdays-drawing?lite

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Tuesday, November 27, 2012

Gunmen free inmates at Nigeria police station

LAGOS, Nigeria (AP) ? Police in Nigeria say gunmen attacked a major police station near the country's capital that is holding members of a radical Islamist sect, freeing some prisoners.

A statement confirmed an attack happened early Monday morning at the Special Anti-Robbery Squad station near Abuja. Federal police spokesman Frank Mba said the gunmen's assault allowed some 30 prisoners to escape. Mba said 25 had already been recaptured.

That station is holding suspected members of the radical Islamist sect known as Boko Haram. Mba denied any Boko Haram members escaped in the attack, though security officials routinely downplay such attacks.

Boko Haram is blamed for killing more than 760 people this year alone. The attack Monday comes after suicide bombings at a church at a military base Sunday killed at least 11.

Source: http://news.yahoo.com/gunmen-free-inmates-nigeria-police-station-134923533.html

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Autism risk for developing children exposed to air pollution: Infant brain may be affected by air quality

ScienceDaily (Nov. 26, 2012) ? Research conducted by University of Southern California (USC) and Children's Hospital Los Angeles scientists demonstrates that polluted air -- whether regional pollution or coming from local traffic sources -- is associated with autism.

The study titled "Traffic Related Air Pollution, Particulate Matter, and Autism," shows that exposure to traffic-related air pollution during pregnancy and the first year of life is associated with a more than two-fold risk of autism. In addition, exposure to regional pollution consisting of nitrogen dioxide (NO2) and small particles -- particulate matter less than 2.5 and 10 microns in diameter (PM2.5 and PM10) -- is also associated with autism even if the mother did not live near a busy road. The study is published in the Archives of General Psychiatry, a sister publication of the Journal of the American Medical Association.

"This work has broad potential public health implications," said the study's principal investigator, Heather Volk, Ph.D., assistant professor of preventive medicine at the Keck School of Medicine of USC and investigator in the Division of Research on Children, Youth and Families at Keck School-affiliated Children's Hospital Los Angeles. "We've known for a long time that air pollution is bad for our lungs, and especially for children. We're now beginning to understand how air pollution may affect the brain."

The research is the first to look at the amount of near-roadway traffic pollution individuals were exposed to and combine that with measures of regional air quality. The study builds on previous research by Volk and colleagues that examined how close subjects lived to a freeway, said Volk, who also has appointments at the Keck School's Zilkha Neurogenetic Institute and Department of Pediatrics.

"We took into account how far away people lived from roads, meteorology such as which way the wind was blowing, how busy the road was, and other factors to study traffic-related pollution," she said. "We also examined data from air quality monitors, which measure pollution over a larger region that could come from traffic, industry, rail yards, or many other sources."

In the 2012 study, Volk and colleagues from USC and the University of California, Davis examined data on 279 autism cases and 245 control subjects enrolled in the California-based Childhood Autism Risks from Genetics and the Environment (CHARGE) study. Mothers' addresses from birth certificates and addresses reported from a residential history were used to estimate exposure during each trimester of pregnancy and the first year of life. The researchers used air pollution levels derived from the Environmental Protection Agency's Air Quality System to determine exposure to NO2, PM2.5, and PM10. They also applied dispersion models to estimate the amount of traffic the mothers and children were exposed to.

Particularly interesting was the effect of mothers' and children's exposure to particles, both PM10 and PM2.5. PM10 includes both coarse and fine particles, while PM2.5 includes only the smaller (fine) particles, which are most likely to have deleterious effects on the human body.

"From studies conducted in the lab, we know that we can breathe in tiny particles and they can produce inflammation," said Volk. "Particles have varied composition, and there are many chemicals that can bind to them. The components of these particles could be hazardous to the brain."

Other researchers who participated in the study include Irva Hertz-Picciotto, University of California, Davis; Rob McConnell from USC; and Fred Lurmann and Bryan Penfold from Sonoma Technology, Inc.

The research was funded by the National Institute of Environmental Health Sciences (grant 1 R21 ES019002-01).

Volk and colleagues are now at work on a study of how genes related to autism may be affected by environmental exposures to try to identify if there are factors that make people are genetically more vulnerable to particular pollutants.

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Story Source:

The above story is reprinted from materials provided by University of Southern California - Health Sciences, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Heather E. Volk et al. Traffic-Related Air Pollution, Particulate Matter, and AutismAir Pollution, Particulate Matter, and Autism. Archives of General Psychiatry, 2012; : 1 DOI: 10.1001/jamapsychiatry.2013.266

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/VtlbBqSqKhA/121126164255.htm

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Tackling 'fragmentation': Developers sound off on supporting multiple screens

Zappos

What does it take to support multiple devices? A few top developers weigh in

Android runs on a variety of devices, which means it also runs on a variety of screen sizes and resolutions. Lots of folks call this "fragmentation." Never mind the fact that they've been using products designed and developed the same way for years on their desktop. Apparently if everything isn't exactly the same it gets the "fragmentation" label. 

There are different ways to tackle the problems that arise when you use screens with different sizes and densities. Apple has separate listings for apps designed for the iPhone versus the iPad. Microsoft creates a new eco-system for its big screen devices. Android provides a way for developers to make the same app work differently for different screens. There's good and bad about each method, but we're going to focus on Android here.

In Android, applications can adjust the layout for different size screens as well as resolution. This is all built in, but there are a few things developers need to declare in their code to make the app look good. The thing to keep in mind is how screen size and density will change the look of the app. The Droid DNA has a higher-res screen than the Motorola XOOM tablet, but we don't want to see a tablet layout for apps on the phone-sized screen.

A developer needs to provide assets (images) that are high enough quality to look sharp at high resolution (never mind insanely high resolution), and be sure to use density independent pixel units when designing their layout. This is what keeps things like buttons and other controls from being really big on low density screens like the Galaxy S2, or from being really tiny on high density screens like the DNA.

It sounds complicated, but most of this stuff is done for you when coding an app. All the developer needs to do is make the right declarations, and provide the right assets to support any size (both physical and resolution) or layout. Even multiple layout apps like the Google+ app use the same code to cover every conceivable screen.

We're not trying to judge developers here. Writing apps is tough. The Android developers have been preaching all this since the release of Gingerbread, but how practical is it? We asked a few developers about it, see what they had to say after the break.

More: Google's Android developer site

read more



Source: http://feedproxy.google.com/~r/androidcentral/~3/LkqzeZJMPFU/story01.htm

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Fostering Curiosity: Mars Express relays rocky images

ScienceDaily (Nov. 26, 2012) ? For the first time, ESA's Mars orbiter has relayed scientific data from NASA's Curiosity rover on the Red Planet's surface. The data included detailed images of 'Rocknest3' and were received by ESA's deep-space antenna in Australia.

It was a small but significant step in interplanetary cooperation between space agencies.

Early on the morning of 6 October, ESA's Mars Express looked down as it orbited the planet, lining up its lander communication antenna to point at Curiosity far below on the surface.

For 15 minutes, the NASA rover transmitted scientific data up to the ESA satellite. A few hours later, Mars Express slewed to point its high-gain antenna toward Earth and began downlinking the precious information to the European Space Operations Centre in Darmstadt, Germany, via the Agency's 35 m-diameter antenna in New Norcia, Australia.

The data were immediately made available to NASA's Jet Propulsion Laboratory in California for processing and analysis, proving again that NASA's amazing new rover can talk with Europe's veteran Mars orbiter.

Curiosity's ChemCam images Rocknest3

The information included a tremendously interesting image acquired on 4 October by Curiosity's ChemCam Remote Micro-Imager camera.

ChemCam comprises the camera together with a Laser-Induced Breakdown Spectrometer, which fires a laser at targets and analyses the chemical composition of the vaporised material.

The laser zaps areas smaller than 1 mm across on the surface of martian rocks and soils, and then the spectrometer provides information on the minerals and microstructures in the rocks.

"The quality of these images from ChemCam is outstanding, and the mosaic image of the spectrometer analyses has been essential for scientific interpretation of the data," says Sylvestre Maurice, Deputy Principal Investigator for ChemCam at France's Research Institute in Astrophysics and Planetology (IRAP).

"This combination of imaging and analysis has demonstrated its potential for future missions."

ChemCam laser targets

A third image, relayed separately by NASA, indicates the locations of the laser target points on Rocknest3, as seen by the RMI camera.

'Rocknest' is the area where Curiosity stopped for a month to perform its first mobile laboratory analyses on soil scooped from a small sand dune. Rocknest3 was a convenient nearby target where ChemCam made more than 30 observations using 1500 laser shots.

A wide-angle context image was acquired by Curiosity's MastCam and shows Rocknest3 as targeted by ChemCam. Rocknest3 is about 10 x 40 cm, or roughly the size of a shoe box.

Fostering Curiosity -- and others

ESA's Mars orbiter has also relayed data for NASA's other surface missions -- Phoenix, Spirit and Opportunity -- since 2004, and it relayed Curiosity's radio signal during its arrival at Mars last August.

During the Curiosity mission, Mars Express is set to provide additional relay slots, while maintaining its own scientific observation programme, under an ESA-NASA support agreement.

It can also rapidly provide relay services in case of unavailability of NASA's own relay orbiter or if there is a problem on the rover itself.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_technology/~3/iqKUdE5FOGY/121126130945.htm

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Monday, November 26, 2012

Onex to buy insurance brokerage from Goldman fund for $2.3 billion

(Reuters) - Canadian private equity firm Onex Corp will buy USI, one of the largest providers of insurance brokerage services in the United States, from Goldman Sachs Group Inc's GS Capital Partners private equity fund for $2.3 billion.

USI, founded in 1994 and taken private in 2007, says it is the ninth largest insurance broker in the United States. It offers property, casualty, employee benefit and retirement consulting services.

Onex Partners III, Onex's $4.7 billion private equity fund, will make an equity investment of about $700 million. Onex is a 25 percent limited partner in Onex Partners III.

Onex, with about $14 billion of assets under management, is a co-investor in the transaction.

USI said its employees, who invested alongside GS Capital Partners to take it private, will remain investors in the company.

The deal is expected to close by the end of the year.

Onex was advised by Morgan Stanley, while GS Capital Partners was advised by Goldman, Sachs & Co and RBC Capital Markets LLC.

(Reporting by Bhaswati Mukhopadhyay in Bangalore)

Source: http://news.yahoo.com/onex-buy-us-insurance-brokerage-services-co-2-121920647--sector.html

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Saturday, November 24, 2012

New drug overcomes resistance in patients with rare sarcoma

Thursday, November 22, 2012

A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber Cancer Institute who led the worldwide clinical trial.

The treatment of gastrointestinal stromal tumor, or GIST, even in its advanced metastatic stage, has been dramatically improved with two oral targeted drugs ? imatinib (Gleevec) and sunitinib (Sutent). To date, these have represented the only two FDA-approved treatments with the proven ability to control GIST. However, in more than 85 percent of patients, GIST becomes resistant to these drugs after seven years and the disease worsens with fatal results.

The new study, whose results are being published in the Lancet, demonstrated that the oral drug regorafenib, which inhibits several cancer-promoting kinase enzymes, was able to control GIST for nearly four months longer than placebo in patients for whom Gleevec and Sutent were no longer effective, a result that was highly significant statistically.

"When added to best supportive care, regorafenib significantly improves disease control, as measured by progression-free survival time in patients with GIST after progression which represents failure of all other therapies," said George Demetri, MD, of Dana-Farber, principal investigator of this clinical trial.

Demonstrating the aggressive nature of this resistant disease, the study found that tumors objectively grew in less than a month, on average, in GIST patients who were initially randomized to receive a placebo. The study's "cross-over" design made it possible to treat those patients whose tumors grew, and 85 percent of the patients initially on placebo were able to receive regorafenib, which then controlled the disease in these patients as well.

Because of the study's cross-over design, Demetri said, it was not expected to prove that the patients initially randomized to receive regorafenib survived longer ? the researchers would have had to withhold the drug from the placebo patients to demonstrate that difference. "But there is no question that people are living longer" with regorafenib treatment, he said, based on the results of this trial.

An application to have regorafenib approved for use in resistant GIST is under an accelerated review by the Food and Drug Administration, Demetri said.

GIST is a rare form of sarcoma that develops in the gastrointestinal tract, mainly in the stomach and small intestine. GIST is estimated to affect more than 5,000 people per year in the United States and about 8,000 in Europe.

Regorafenib is a novel rationally designed drug manufactured by Bayer HealthCare Pharmaceuticals that was FDA-approved in September 2012 to treat metastatic colon cancer after failure of standard chemotherapy. It blocks several cancer-promoting enzymes called kinases, which spur runaway growth in GIST and other cancers.

The phase 3 international trial involved 199 treatment-resistant GIST patients at 57 hospitals in 176 countries. Of the 199 patients, 133 received a regorafenib pill daily for three weeks followed by a one-week break, while 66 received a matching placebo. The patients were monitored for at least one year after the trial began.

As for other targeted therapies, the drug did not often shrink tumors but controlled the disease for an average of 4.8 months before it progressed, while patients in the placebo group experienced less than one month (0.9 month) before the disease worsened. There was a high rate of adverse effects including high blood pressure, fatigue, diarrhea, and redness, swelling, numbness and peeling of skin on the hands and feet. These side effects were managed by reducing or interrupting the regorafenib treatment, the report said.

A companion report in The Lancet said that the drug had a "modest" benefit in patients with metastatic colon cancer. A commentary by David Cunningham, MD, of the Royal Marsden Hospital in England, said, "In the relatively rare GIST, the case for routine use of this drug in patients following failure of existing treatments is strong."

Demetri added "We know that regorafenib can inhibit many of the mutated proteins and abnormal signals that cause this cancer, and the next step will be to investigate the molecular mechanisms by which this new treatment can control GIST after resistance appears to other 'targeted therapy' drugs for this aggressive malignancy."

The clinical trial was supported, in part, by Bayer HealthCare Pharmaceuticals, as well as the Ludwig Center at Dana-Farber/Harvard Cancer Center.

###

Dana-Farber Cancer Institute: http://www.dfci.harvard.edu

Thanks to Dana-Farber Cancer Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125439/New_drug_overcomes_resistance_in_patients_with_rare_sarcoma

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Thursday, November 22, 2012

Factories post rebound, consumer sentiment shaky

WASHINGTON (Reuters) - Manufacturing grew in November at its quickest pace in five months, with a rise in domestic demand hinting that factories could provide a boost to economic growth in the fourth quarter.

Other data on Wednesday showed a drop in new claims for jobless benefits, although they remained elevated due to superstorm Sandy, and only a marginal improvement in consumer sentiment.

Financial information firm Markit said its U.S. "flash," or preliminary, manufacturing Purchasing Managers Index rose to 52.4 from a three-year low of 51.0 in October. A reading above 50 points to growth in the factory sector.

Still, economists cautioned against taking the reading at face value as other gauges of manufacturing have looked softer, including readings for new orders and regional business sentiment surveys.

"We're still not exactly going gangbusters," said Sarah Watt, an analyst at Wells Fargo in Charlotte, North Carolina. "The data point to modest growth."

Economists expect U.S. economic growth will slow in the fourth quarter to a lackluster 1.6 percent annual rate from a 2.0 percent rate in the prior three months, according to a Reuters poll conducted on November 15.

Some respondents in Markit's survey said efforts to rebuild after Sandy may have accounted for some of the increased demand.

The storm continues to make it more difficult to read the underlying health of the economy. Jobless claims surged after the deadly storm hit the U.S. East Coast on October 29 but last week retraced about half of that rise. Factory output and retail sales contracted last month, largely due to the storm.

Most of these effects are expected to be temporary, but even taking that into account, the U.S. economy appears to be stuck in low gear. Europe's debt crisis is weighing on the global economy and U.S. businesses appear hesitant to ramp up hiring and investment with the government on course to slash the country's budget deficit next year.

"Stripping out the short-term boost from Sandy ... and (factory) output is probably flat," said Paul Dales, an economist with Capital Economics in London. "That's unlikely to change much when the global economy is set to remain weak."

THROUGH THE EYE OF THE STORM

The Labor Department said initial claims for state unemployment benefits dropped 41,000 to a seasonally adjusted 410,000. Sandy had driven first-time filings up by 90,000 in the prior week.

Economists said that while the still-high level of claims reflected the storm's impact, it also likely pointed to more fundamental problems in the jobs market.

"There appears to be a noticeable deceleration of growth in the fourth quarter," said Peter Hooper, an economist at Deutsche Bank in New York. "It would not be surprising if some of the new jobless claims are due to underlying weakness," he said.

U.S. financial markets showed little reaction to the data as investors focused on developments in Europe and trading slowed ahead of the Thanksgiving holiday on Thursday. U.S. stocks rose, while Treasury debt prices were down modestly.

The claims report covered the same week when the Labor Department collects data for its estimate on hiring in November. It suggested that report, due on December 7, could prove soft, although not all analysts expect a significant storm impact. Nonfarm payrolls grew 171,000 in October.

"We are expecting things to be in the neighborhood of what we have seen, maybe with a pullback in light of the hurricane," said Bricklin Dwyer, an economist at BNP Paribas in New York.

CONSUMER SPIRIT

Growth in the U.S. economy has looked uneven in recent months, with business investment sagging due to fears about U.S. fiscal policy, while consumer spending and the housing market have shown some strength.

At the end of November, several months of improvement in U.S. consumer sentiment stalled as uncertainty grew over whether lawmakers would steer clear of planned tax hikes and government spending cuts, a survey showed.

The Thomson Reuters/University of Michigan's final November reading on the overall index on consumer sentiment came in at 82.7, a touch up from 82.6 the month before, but down from a preliminary reading of 84.9 released earlier in the month.

Separately, a gauge of future U.S. economic activity rose marginally in October, pointing to modest near-term growth.

"Based on the trends, the economy will continue to expand modestly through the early months of 2013," said Ken Goldstein, an economist at the Conference Board, which released the report.

Other data showed applications for U.S. home mortgages eased last week, though demand for new loans improved.

(Additional reporting by Steven C. Johnson, Edward Krudy, Ellen Freilich and Richard Leong in New York; further reporting by Lucia Mutikani in Washington; Editing by Andrea Ricci)

Source: http://news.yahoo.com/jobless-claims-drop-factories-post-rebound-141821662--business.html

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Wednesday, November 21, 2012

Large blast hits diplomatic area of Afghan capital

KABUL (Reuters) - A large blast that was most likely a suicide bomb attack ripped through the heavily barricaded diplomatic area of the Afghan capital Kabul on Wednesday, a police official said, and there were an unknown number of casualties.

"Around 8 o'clock today there appeared to be a suicide bomb attack ... We cannot say what the target was at this point in time," said Hashmatullah Stanikzai, a spokesman for Kabul Police.

Stanikzai said it was not immediately clear how many people had been killed or wounded, but there were casualties.

Embassy sirens sounded and ambulances could be heard after the blast, which happened in the area where the U.S. and British embassies and the headquarters of the NATO-led International Security Assistance Force (ISAF) are located.

A spokesman for ISAF said the coalition was aware of an explosion.

(Reporting by Amie Ferris-Rotman and Mirwais Harooni; Editing by Paul Tait)

Source: http://news.yahoo.com/large-blast-heard-diplomatic-area-afghan-capital-witnesses-040222965.html

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U.N. cannot confirm reports of Congo shelling into Rwanda

Robert Lieberman, the maker of the critically acclaimed documentary, They Call It Myanmar ? Lifting the Curtain, tells a story that exposes some of the cynical reality behind President Obama?s historic visit to politically imprisoned Myanmar today. Shortly after Aung San Suu Kyi, the Nobel Prize-winning democracy activist, was released from two decades of house arrest in November of 2010, Lieberman was invited to show his film at a Yangon festival that Suu Kyi was organizing called ?The Art of Freedom.? Thoughtfully, he informed the U.S. Embassy of his plans. Their reaction? Near-panic.

Source: http://news.yahoo.com/u-n-cannot-confirm-reports-congo-shelling-rwanda-183657543.html

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News Corp Is Buying Companies - Business Insider

Jay Yarow | Nov. 20, 2012, 1:16 PM | 944| Tweet Email Share on Tumblr

We got a nice note from News Corp asking us to let you know that they're now aggressively looking to buy companies.

(We're not sure why they want you to know that, but they do.)

So tee up your pitch decks!

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'; } else if (google_ads[0].type == "image") { s += ''; } else if (google_ads[0].type == "html") { s += google_ads[0].snippet; } else { if (google_ads.length == 1) { /* * Partners should adjust text sizes * so ads occupy the majority of ad space. */ s += ' ' + google_ads[0].line1 + '
' + google_ads[0].line2 + '?' + google_ads[0].line3 + '
' + google_ads[0].visible_url + '

'; } else if (google_ads.length > 1) { /* * For text ads, append each ad to the string. */ for(i = 0; i

Source: http://www.businessinsider.com/news-corp-is-buying-companies-2012-11

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Tuesday, November 20, 2012

Best Deal Site?

Best Deal Site? The holiday shopping season is about to kick off, and now's the time to start thinking about how you can get everyone on your list something great without going broke in the process. You're a smart shopper, so you probably have plenty of deal sites you use to get he best bang for your buck, whether you're holiday shopping or buying any time of year. This week we want to know which money-saving deal sites you turn to.

We're a little early with our call for contenders this week so we can get you the results in time for Cyber Monday, so you can go in ready to save some cash. There are more deal sites than ever, and they all offer great discounts, but which ones do you turn to when you want current, deep discounts on a variety of categories? Only a few can stand above the rest, so leave us your nominations in the discussions below.

Hive Five nominations take place in the discussions, where you post your favorite tool for the job. We get hundreds of nominations, so to make your nomination clear, please include it at the top of your comment like so: VOTE: BEST DEAL SITE. Please don't include your vote in a reply to another person. Nominations emailed to us will not be counted. Instead, make your vote and reply separate discussions. After you've made your nomination, let us know what makes it stand out from the competition.

About the Hive Five: The Hive Five feature series asks readers to answer the most frequently asked question we get: "Which tool is the best?" Once a week we'll put out a call for contenders looking for the best solution to a certain problem, then YOU tell us your favorite tools to get the job done. Every weekend, we'll report back with the top five recommendations and give you a chance to vote on which is best. For an example, check out last week's five best webcams.

The Hive Five is based on reader nominations. As with most Hive Five posts, if your favorite was left out, it's not because we hate it?it's because it didn't get the nominations required in the call for contenders post to make the top five. We understand it's a bit of a popularity contest, but if you have a favorite, we want to hear about it. Have a suggestion for the Hive Five? Send us an email at tips+hivefive@lifehacker.com!

Photo by Tim Parkinson.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/UnsvGdWBfUU/best-deal-site

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Monday, November 19, 2012

Amazon Kindle celebrates five e-inked years

Amazon Kindle celebrates five einked years

Can you imagine a holiday season without Amazon's e-reader series? The Kindle celebrates its fifth birthday today -- a device that, since its debut, has added bigger screens, slimmer builds, and even some damn decent backlighting. Back at the start, Amazon's first hardware was just a little chunky, covered in buttons, and housed a 6-inch 800 x 600 e-ink display. However, the online bookseller went on to dominate the then-nascent e-reader market, with no shortage of rivals now wanting claim their own slice of the book-loving crowd. Five years goes pretty fast -- we just wonder how many still have their DRM-protected Mobipocket e-books to hand.

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Amazon Kindle celebrates five e-inked years originally appeared on Engadget on Mon, 19 Nov 2012 07:46:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/11/19/amazon-kindle-turns-five-birthday/

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From commmunity college deciding between transfer W&M and OOS Private University

From commmunity college deciding between transfer W&M and OOS Private University


Hello, I'm an 18 year old female from NOVA Community College, trying to decide between William & Mary, and other out of state universities including USC, Emory, & Cornell. When i grow up, my main career aspiration is to do something in marketing, especially in the entertainment industry, but ever since i was little people have told me i'm gonna be famous, and i love to act, do comedy, and would love to model. I'm obviously not at the point where i would leave college to go straight into the industry, but it's something i've always wanted to do, i don't feel like a normal 9-5 job is for me. That being said, I'm planning on going to W&M on guaranteed admissions agreement with a 3.6, and then applying to their business program. W&M is in-state, and has the best tuition and from what i hear a good business program for marketing, but i just feel like there isn't anything there for me, i really wanna love it but i don't know if i'll gain anything from there, but maybe im just being naive. So knowing i'm moving to California after college pretty much regardless, should i just go to W&M and then go to LA after im finished with college? I feel like another college would be more enjoyable, because i'm more interested in making connections, friends, and getting experience, such as taking acting classes on the side, and i would love being near such a big city and all it has to offer during college and having that typical "moving to california then making it big" stories, but obviously that's only a small chance. But at the same time, i'm really smart, i got a 4.0 in highschool but chose to go to CC to save money and transfer , so i can get any education i need. I'm just finding it hard to justify going to W&M, do they have any connections to the entertainment industry? I also can't afford any private schools at the same time. So what should i do? should i go to W&M and wait until im 22 to go to LA? Or should i find a way to go to a big city despite all the obstacles? Or does anyone know any good schools that would fit me. AND is it even possible to get into all these schools assuming ill have a 3.6+ either way

Source: http://talk.collegeconfidential.com/college-search-selection/1417524-commmunity-college-deciding-between-transfer-w-m-oos-private-university.html

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Personally, I love my mac for the customer service, video watching and the fact that I switched to apple so long ago that PC's confuse me a little bit now. But! I don't know how art programs work -- I know my brother does some graphic design on his, but I'

Perpetually Caffeinated ? Personally, I love my mac for the customer service, video watching and the fact that I switched to apple so long ago that PC?s confuse me a little bit now. But! I don?t know how art programs work ? I know my brother does some graphic design on his, but I?m pretty sure he got programs for free from his university. (And I don?t know if those would even be the sorts of programs you?re interested in.) So, as a general rule, if you?re not unhappy, why change? But I do love my mac.

Source: http://perpetuallycaffeinated.tumblr.com/post/35989550286

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